Discover the latest articles and news in related subjects. These data indicate that Sara endosomes and/or Delta and Notch therein determine the Notch signalling level of the recipient cell. Because ...

为探究 Mib1 与 Delta 的作用机制，研究人员进行体内实验，揭示相关规则，助力理解 Notch 信号通路。 探秘 Notch 信号通路：Delta 配体激活机制的深度解析 在生命的微观世界里，细胞间的信号传导如同精密的交响乐，每一个音符都至关重要。Notch 信号通路便是其中 ...

While the role of barrier function in establishing a protective, nutrient-rich, and ionically balanced environment for neurons has been appreciated for some time, little is known about how signaling ...

研究人员针对形态创新（morphological novelty）的进化机制这一核心问题，以果蝇雄性生殖器后叶（posterior lobe）这一新结构为模型，揭示了Notch信号通路配体Delta通过增强子进化获得新功能的分子机制。研究发现Delta信号中心源于生殖盘外翻（genital disc eversion）的 ...

Scientists from the department of Anatomy and Embryology at the Faculty of Medicine of the University of Tsukuba created a computer model to simulate the development of complex structures based on the ...

A report in the January 24 online Journal of Biological Chemistry indicates that the Notch ligands Delta and Jagged are also substrates for γ-secretase, the intramembrane aspartyl protease responsible ...