Researchers at Kanazawa University and the National Institute of Genetics in Japan have used high-speed atomic force ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells. This new structural and ...

Single-molecule techniques have advanced our understanding of DNA–protein interactions, yet simultaneously tracking enzyme position on DNA, determining binding dynamics and resolving enzyme activity ...

Penn State researchers found that cancer-linked BRD4 can bind nucleosomes through both DNA contacts and recognition of ...

Determining protein structures requires crystals, but getting proteins to crystallize has long depended on a slow, unpredictable process of trial and error ...

Structure-guided screening has yielded two compounds that selectively interfere with CDCA7 binding to hemi-methylated DNA, ...

A new artificial intelligence model can predict how different proteins may bind to DNA. A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how ...

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins - ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

David Baker, Demis Hassabis and John M. Jumper shared the Nobel Prize in Chemistry on Wednesday for their work on protein structure. Atila Altuntas / Anadolu via Getty Images On Wednesday morning, ...